Current
Erlangen, 15. May 2019
AB-CT at CERN
AB-CT performed at 5th Workshop on Medical Applications of Spectroscopic X-ray Detectors, 13-16 May 2019, CERN, Geneva, Switzerland
The workshop focused sharply on all aspects of the medical applications of spectroscopic X-ray detectors by inviting experts in the various domains which contribute to the development of the field. Clinicians, radiologists, biologists, tracer developers, imaging system specialists and detector and ASIC developers exchanged information and knowledge about the latest developments.
Daniel Kolditz, CTO of AB-CT, gave a lecture on the topic: Technical characteristics and initial clinical patient results of a photon-counting spiral breast-CT system.
Abstract:
Technical overview of the photon-counting breast CT system and its performance, the first clinical patient results and an outlook of potential applications.
Photon-counting spiral breast computed tomography (BCT) is a novel approach in breast imaging. It provides high resolution at very low dose using novel direct-conversion photon-counting detector technology combined with a spiral CT acquisition concept. The system (type nu:view, AB-CT – Advanced Breast-CT GmbH, Erlangen, Germany) presented here has received CE mark in 2018 and is available in clinical use. Performance tests showed a superior image quality compared to mammography, breast tomosynthesis, clinical CT as well as cone-beam breast CT systems based on conventional indirect converting X-ray detectors. The first clinical results confirm that the superposition-free 3D images are optimal for soft-tissue differentiation and micro-calcification characterization and this at dose level of mammography.
Erlangen, 29. April 2019
100. Deutscher Röntgenkongress
Besuchen Sie uns auf dem 100. Deutschen Röntgenkongress
- Congress Center Leipzig
- 29.05.2019 – 01.06.2019
- Halle 2, Stand A30
Erfahren Sie mehr über nu:view – den weltweit ersten Brust-CT-Scanner, der auf Spiral-CT-Technologie basiert
Trotz modernster Technologie und gut ausgebildeter Radiologen gilt die frühzeitige und verlässliche Brustkrebsdiagnose weiterhin als Herausforderung. Herkömmliche Diagnoseverfahren sind etabliert, aber nicht immer verlässlich. 3D-Aufnahmen mit hoher isotroper Auflösung hingegen bieten signifikante Vorteile.
nu:view ist der weltweit ersten Brust-CT Scanner, der auf Spiral-CT Technologie basiert. Er zeichnet sich durch eine sehr hohe Bildauflösung bei niedriger Strahlendosis und eine kurze Aufnahmezeit aus. Um bestmögliche Bildqualität bei höchster Dosiseffizienz zu erreichen werden beim Detektor modernste Single Photon Counting Technologien eingesetzt.
„Die Bilder sehen überzeugend aus, die Bildqualität ist hervorragend. Die dreidimensionalen, überlagerungsfreien Aufnahmen erleichtern im Vergleich zur Mammografie den Nachweis von Mikrokalzifikationen erheblich. Die kompressionsfreie Untersuchung erhöht nicht nur den Komfort für die Patientin, sie reduziert auch die Anzahl zusätzlicher Ultraschallaufnahmen.“ (Prof. Dr. Andreas Boss, Leitender Arzt im Institut für diagnostische und interventionelle Radiologie am USZ und erster Anwender des nu:view).
Überzeugen Sie sich selbst von der einzigartigen Bildqualität und besuchen Sie uns am Stand A30.
Erlangen, 17. April 2019
Symposium zum Thema: 30 Jahre “Spiral-CT”
Anlässlich des 100. Deutschen Röntgenkongresses gibt Willi A. Kalender, Gründer und wissenschaftlicher Berater der AB-CT – Advanced Breast-CT GmbH, eine Übersicht zum Stand der Forschung und Entwicklung auf dem Gebiet der Spiral-CT-Technik und -Anwendungen.
30 Jahre Spiral-CT mit bahnbrechenden technologischen Entwicklungen und positiven klinischen Ergebnissen für die Radiologie und für die Patienten.
Wir laden Sie herzlich zum Symposium “Spektral-Detektor-CT” ein. Erfahren Sie mehr über die Entwicklung des Spiral-CTs während drei Jahrzehnten.
| Datum: | Freitag, 31. Mai 2019 |
| Uhrzeit: | 13:45 – 15:25 |
| Ort: | CCL – Congress Centrum Leipzig – Raum: Hellmann |
| Sprache: | Deutsch |
Sie finden uns in Halle 2, Stand A30.
Wir freuen uns auf Ihren Besuch in Leipzig.
15. April 2019
Next Generation Medicine – Alternative zur Mammographie
Ein Gespräch zwischen Prof. Dr. med. Andreas Boss aus dem Universitätsspital Zürich und Dr. med. Dr. phil. Anna Erat.
Prof. Dr. med. Andreas Boss, erster Anwender von nu:view, dem Spiral Computertomographen für die Darstellung der weiblichen Brust, informiert in einem kurzem Interview über die Funktionsweise und Vorzüge des Brust-CTs.
Erlangen, 21. March 2019
Dedicated breast CT shows promise for cancer screening
A dedicated breast CT scanner that features a photon-counting detector produces high-quality images at a low radiation dose. The findings indicate that the CT scanner could be a useful tool for breast cancer screening, according to a study published online March 2 in Investigative Radiology.
In fact, a team from the University of Zurich in Switzerland believes that breast CT has the potential to further improve breast lesion detection and characterization compared with mammography and digital breast tomosynthesis — particularly because it does not require breast compression, and the photon-counting detector technology reduces radiation dose to levels comparable to those of a conventional mammogram.
“Previous studies investigating the use of conebeam breast CT in comparison to mammography reported higher radiation doses for breast CT, especially when referring to a screening setting,” wrote a group led by Dr. Nicole Berger. “More recently, new strategies have strongly increased the dose efficiency due to the use of novel photon-counting detector technology, resulting in dose levels for breast CT comparable to those of screening mammography or lower.”
Yet another benefit to breast CT is that it can be used with contrast, Berger and colleagues wrote.
“The possibility to perform contrast-enhanced examinations indicates a possible usage of breast CT comparable to breast MR imaging with the additional capability to simultaneously detect microcalcifications and soft-tissue contrast enhancement,” the researchers noted.
Holy grail?
Researchers continue to seek ways to screen for breast cancer that will minimize potential harms and maximize benefits, and Berger’s team is no different. This study used data from start-up firm Advanced Breast-CT’s dedicated spiral breast CT system, nu:view, which has a photon-counting detector based on cadmium telluride (CdTe) crystals. It’s the first clinical in vivo application of nu:view, which received CE Mark certification in September of last year.
Questions have arisen as to whether the resolution of breast CT is high enough to depict microcalcifications. The new detectors address this concern.
“Up to now, resolution of breast CT did not reach high enough resolution to visualize microcalcifications, which the new dedicated breast CT can provide. … The high resolution, but also the possibility to evaluate the images in different planes, increases and facilitates the characterization of lesions regarding suspicious features such as conspicuity, calcifications, and asymmetries, as well as masses,” the researchers wrote.
For the current study, 12 women referred for breast cancer screening underwent bilateral breast CT in the prone position as well as breast ultrasound. Three of the 12 women had previous mammography available for comparison.
Two radiologists interpreted 15 breast CT exams, which they evaluated for image quality using the following measures: spatial resolution, contrast resolution, signal-to-noise ratio, and contrast-to-noise ratio. The researchers used final reports from the breast CT evaluations with ultrasound assessment as the reference standard.
Finally, study participants gave feedback about both positioning and overall comfort during the exam using a scale of 1 to 5 (with 5 equal to maximum comfort).
The major pectoral muscle was included in 15 breast CT scans (62.5%); a glandular component was partially missing in two (8.3%) of the 24 scanned breasts. Berger’s group found a “ring” artifact in all scans, although it did not influence image interpretations.
Breast CT identified three masses that were confirmed to be simple cysts on ultrasound. Ultrasound identified another five simple cysts and two solid benign lesions. In all of the breast CT exams, 12 calcifications were identified, with a median size of 1.1 mm; both readers identified all three masses and 11 of 12 calcifications on breast CT.
As for the women’s feedback about the comfort of the exam, the majority (75%) ranked it a 4 on a scale of 1 to 5; all women with prior mammography ranked the breast CT exam as more comfortable due to the absence of compression.
With respect to radiation dose, Monte Carlo simulations on phantoms found that mean dose was in the range of 5.08 mGy. For point of comparison, Hendrick et al in 2010 found radiation dose from two-view digital mammography of 3.7 mGy and for film-screen mammography of 4.7 mGy.
“The new dedicated spiral breast CT equipped with a photon-counting detector provides high-quality images at low radiation dose and shows considerable potential for screening and diagnosis of breast cancer, along with improved patient comfort compared with conventional mammography,” Berger and colleagues concluded.
Source: AuntMinnie
Erlangen, 24. January 2019
EUSOBI Mammography & beyond Course
Theoretical lectures will be enhanced by hands-on workshops on systems provided by different vendors.
There will be several Hands-On Sessions:
First hand experience reading Breast CT images – best practices from University Hospital Zurich
given by Andreas Boss, PD Dr. Dr. (USZ, Institute of Diagnostic and Interventional Radiology)
Get the course program here
The course has limited access in order to ensure that each participant has the possibilty to work with different MG based techniques.
Erlangen,
ECR 2019
Erlangen, 22. November 2018
RSNA 2018
Erlangen, 21. September 2018
nu:view Granted CE Certification
Even with high-tech technology and skilled, qualified radiologists, early and reliable diagnosis of breast cancer remains challenging. According to the German Cancer Research Center in Heidelberg, some 69,000 women in Germany are diagnosed with breast cancer every year, with almost 18,000 dying of the disease. Conventional diagnosis methods, while well established, are not always reliable. 3D imaging with high isotropic resolution, on the other hand, offers clear advantages.
nu:view, the world’s first breast CT scanner to use spiral CT technology, is the brainchild of Erlangen-based company AB-CT. With the CE marking for nu:view in place, the new scanner is already in use on patients at the University Hospital Zurich (USZ).
What sets nu:view apart is the very high image resolution coupled with low radiation dose and short scan times, explains AB-CT CEO Benjamin Kalender, referring to the benefits of the new CT scanner. “To obtain the best possible image quality and maximize radiation dose efficiency at the same time, the detector uses state-of-the-art single photon counting technology.” Unlike conventional scintillation, nu:view uses detectors made of cadmium telluride (CdTe), transforming every x-ray photon directly into an electric pulse.
In a single rotation around the female breast, 2,000 projection images are created, with a full scan taking as little as seven to 12 seconds—at very low radiation levels without breast compression, ensuring excellent patient comfort. “For the first time we have a CT scanner that makes it possible to acquire an image of the entire female breast in a single scan in true 3D, imaging both the soft tissue and the calcifications,” the CEO explains.
Prof. Dr. Andreas Boss, senior consultant for breast imaging at the Institute for Diagnostic and Interventional Radiology at University Hospital Zurich and first user of nu:view, can attest to its merits: “The images are impressive; the image quality is excellent. Compared to mammography, the three dimensional, non-superimposed images make it far easier to detect micro-calcifications. This non-compressive method also means less discomfort for the patient and reduces the number of additional ultrasound images into the bargain.”
7. May 2018
Opening Symposium
You’re cordially invited to join the Opening Symposium “Entwicklung der Computertomographie im Hinblick auf das Jahr 2020”
Prof. Willi Kalender will give a lecture on “Spiral-CT der Brust mit hoher Ortsauflösung und niedriger Dosis”
Please join our session and take the opportunity to discuss the game changing results:
Date: Wednesday, 09-May-18
Time: 13:00
Place: Raum Levy-Dorn CCL Ebene +2 Leipzig
Language: German
You will find our booth at Hall2, Booth C20
We are looking forward to seeing you at Leipzig
7. February 2018
AB-CT at ECR
Austria Center Vienna (ACV)
Join us at Expo X1, Booth 165
Thursday, March 1, 2018 at 8:30am – 10:00am
Join Prof. Willi Kalender (our Founder and Scientific Advisor) during the joint session of the ESR and EFOMP as he discusses CT breast imaging. Learn about early efforts of CT imaging of breast tissue.
See image quality requirements for improving breast cancer diagnosis. Understand the importance of advanced detector technology for the low-dose, high- resolution breast CT. Compare the difference between CT imaging and other forms of breast imaging such as, digital mammography and breast tomosynthesis.
Erlangen, 16. November 2017
Visit us at RSNA – Nov 26 – Dec 1, 2017
This year AB-CT – Advanced Breast-CT GmbH will have a booth at RSNA’s Annual Meeting. You will have the opportunity to meet our Senior Management Team (CEO, CFO, CTO) and discuss the benefits of our disruptive technology.
You can even schedule an appointment with Prof. Willi Kalender, PhD our Founder and Scientific Advisor.
Grab this opportunity and visit our booth South – Hall A: 2565C (German Pavilion)
Looking forward to meeting you at RSNA 2017
Washington, DC, 15. November 2017
National Academy of Engineering Elects 80 Members and 22 Foreign Members
Erlangen,
CT pioneers spell out how to reduce patients’ anxiety over dose
Contact us
AB-CT – Advanced Breast-CT GmbH
91052 Erlangen
Germany